Nathalie is a female given name. It is a variant of the name Natalie/Natalia which is found in many languages, and is especially common in French and English speaking countries.

Notable people with the name include:

• Nathalie, Italian singer
• Nathalie Baye, French actress
• Nathalie Boltt, South African actress
• Nathalie Carrasco, French chemist and professor of astronomy and astrophysics
• Nathalie Dechy, French former tennis player
• Nathalie Delon (1941–2021), French actress and film director
• Nathalie Doummar, Canadian playwright and actress
• Nathalie Eisenbaum, French mathematician
• Nathalie Emmanuel, British actress
• Nathalie Ferlut, French comics cartoonist
• Nathalie Kelley, Peruvian-Australian actress
• Nathalie Lahdenmäki, Finnish ceramic artist and designer
• Nathalie Schenck Laimbeer, American banker
• Nathalie Lind (1918–1999), Danish politician
• Nathalie Loriers, Belgian jazz pianist and composer
• Nathalie Lupino, French judoka
• Nathalie Makoma, Dutch singer, runner-up in the Dutch TV series Idols 4
• Nathalie Matar, Lebanese footballer
• Nathalie Palanque-Delabrouille, French astrophysicist, cosmologist
• Nathalie Paulding, American actress
• Nathalie Roussel, French actress
• Nathalie Simard, Canadian singer
• Nathalie Sarraute, Russian-born French writer
• Nathalie Stutzmann, French contralto and conductor
• Nathalie Tauziat, French former tennis player
• Nathalie Vierin, Italian tennis player
• Natalie Zahle, Danish reform pedagogue